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PMC Biophysics

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  1. Content type: Research

    The various lamellar phases of dipalmitoylphosphadtidylcholine bilayers with and without cholesterol were used to assess the versatility of the fluorescent probe merocyanine 540 through simultaneous measuremen...

    Authors: Hannabeth A Franchino, Brett C Johnson, Steven K Neeley, Rajeev B Tajhya, Mai P Vu, Heather A Wilson-Ashworth and John D Bell

    Citation: PMC Biophysics 2010 3:14

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  2. Content type: Problem

    Lipids undergo self-assembly to form ordered nonlamellar, nanoperiodic arrays both in vitro and in vivo. While engineering of such membrane arrays for technical devices is envisaged, we know little about their...

    Authors: Siegfried Reipert, Józefa Wesierska-Gadek and Sebastian Wienerroither

    Citation: PMC Biophysics 2010 3:13

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  3. Content type: Letter

    Multi-color fluorescence imaging experiments of wave forming Dictyostelium cells have revealed that actin waves separate two domains of the cell cortex that differ in their actin structure and phosphoinositide co...

    Authors: Carsten Beta

    Citation: PMC Biophysics 2010 3:12

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  4. Content type: Research article

    Cry4Aa toxin is one of the highly specific mosquito-larvicidal proteins produced by the bacterium Bacillus thuringiensis subspecies israelensis. It is thought to form pores in the larval midgut membrane that caus...

    Authors: Taveechai Taveecharoenkool, Chanan Angsuthanasombat and Chalermpol Kanchanawarin

    Citation: PMC Biophysics 2010 3:10

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  5. Content type: Research article

    Eukaryotic cell flattening is valuable for improving microscopic observations, ranging from bright field (BF) to total internal reflection fluorescence (TIRF) microscopy. Fundamental processes, such as mitosis...

    Authors: Christian Westendorf, Albert J Bae, Christoph Erlenkamper, Edouard Galland, Carl Franck, Eberhard Bodenschatz and Carsten Beta

    Citation: PMC Biophysics 2010 3:9

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  6. Content type: Research article

    Polymerization of actin into filaments can push membranes forming extensions like filopodia or lamellipodia, which are important during processes such as cell motility and phagocytosis. Similarly, small organe...

    Authors: Mikhail Kudryashev, Simone Lepper, Wolfgang Baumeister, Marek Cyrklaff and Friedrich Frischknecht

    Citation: PMC Biophysics 2010 3:6

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  7. Content type: Research article

    The voltage-dependent anion channel (VDAC, also known as mitochondrial porin) is the major transport channel mediating the transport of metabolites, including ATP, across the mitochondrial outer membrane. Bioc...

    Authors: Daniel Neumann, Johanna Bückers, Lars Kastrup, Stefan W Hell and Stefan Jakobs

    Citation: PMC Biophysics 2010 3:4

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  8. Content type: Research article

    Cellular oxygen sensing is fundamental to all mammalian cells to adequately respond to a shortage of oxygen by increasing the expression of genes that will ensure energy homeostasis. The transcription factor H...

    Authors: Christoph Wotzlaw, Silke Gneuss, Rebecca Konietzny and Joachim Fandrey

    Citation: PMC Biophysics 2010 3:5

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  9. Content type: Research article

    The mammalian cell nucleus contains a variety of organelles or nuclear bodies which contribute to key nuclear functions. Promyelocytic leukemia nuclear bodies (PML NBs) are involved in the regulation of apopto...

    Authors: Peter Brand, Thorsten Lenser and Peter Hemmerich

    Citation: PMC Biophysics 2010 3:3

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  10. Content type: Research article

    Ca2+ binding proteins are essential for regulating the role of Ca2+ in cell signaling and maintaining Ca2+ homeostasis. Negatively charged residues such as Asp and Glu are often found in Ca2+ binding proteins and...

    Authors: Anna Wilkins Maniccia, Wei Yang, Julian A Johnson, Shunyi Li, Harianto Tjong, Huan-Xiang Zhou, Lev A Shaket and Jenny J Yang

    Citation: PMC Biophysics 2009 2:11

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  11. Content type: Research article

    Nanosecond, megavolt-per-meter electric pulses cause permeabilization of cells to small molecules, programmed cell death (apoptosis) in tumor cells, and are under evaluation as a treatment for skin cancer. We ...

    Authors: Meng-Tse Chen, Chunqi Jiang, P Thomas Vernier, Yu-Hsuan Wu and Martin A Gundersen

    Citation: PMC Biophysics 2009 2:9

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  12. Content type: Research article

    FtsZ is a GTPase that assembles at midcell into a dynamic ring that constricts the membrane to induce cell division in the majority of bacteria, in many archea and several organelles. In vitro, FtsZ polymerize...

    Authors: Alfonso Paez, Pablo Mateos-Gil, Ines Hörger, Jesús Mingorance, Germán Rivas, Miguel Vicente, Marisela Vélez and Pedro Tarazona

    Citation: PMC Biophysics 2009 2:8

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  13. Content type: Research article

    Exposure of human erythrocytes to elevated intracellular calcium causes fragments of the cell membrane to be shed as microvesicles. This study tested the hypothesis that microvesicle release depends on microsc...

    Authors: Laurie J Gonzalez, Elizabeth Gibbons, Rachel W Bailey, Jeremy Fairbourn, Thaothanh Nguyen, Samantha K Smith, Katrina B Best, Jennifer Nelson, Allan M Judd and John D Bell

    Citation: PMC Biophysics 2009 2:7

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  14. Content type: Research article

    The acidic C-terminal peptides from Trypanosoma cruzi ribosomal P proteins are the major target of the antibody response in patients suffering Chagas chronic heart disease. It has been proposed that the disease i...

    Authors: Osvaldo A Martín, Myriam E Villegas and Carlos F Aguilar

    Citation: PMC Biophysics 2009 2:4

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  15. Content type: Mini-review

    Lipids, the building blocks of cells, common to every living organisms, have the propensity to self-assemble into well-defined structures over short and long-range spatial scales. The driving forces have their...

    Authors: Guillaume Tresset

    Citation: PMC Biophysics 2009 2:3

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  16. Content type: Research article

    We describe and test an implicit solvent all-atom potential for simulations of protein folding and aggregation. The potential is developed through studies of structural and thermodynamic properties of 17 pepti...

    Authors: Anders Irbäck, Simon Mitternacht and Sandipan Mohanty

    Citation: PMC Biophysics 2009 2:2

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  17. Content type: Research article

    Correlation of lipid disorder with membrane protein dynamics has been studied with infrared spectroscopy, by combining data characterizing lipid phase, protein structure and, via hydrogen-deuterium (H/D) excha...

    Authors: Balázs Szalontai

    Citation: PMC Biophysics 2009 2:1

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