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Figure 3 | PMC Biophysics

Figure 3

From: Two-color STED microscopy reveals different degrees of colocalization between hexokinase-I and the three human VDAC isoforms

Figure 3

Distinct sub-mitochondrial distributions of the three hVDAC isoforms. Confocal microscopy of immunolabeled cultured human U2OS cells. Green: Different hVDAC isoforms, as indicated. For visualization, the respective Flag-tag fusion proteins were decorated with an antiserum against the Flag-peptide. Red: Mitochondria, highlighted with antibodies against the mitochondrial protein Tom20. Blue: Nucleus, stained with DAPI. The close-ups of the overlays show that hVDAC1 and hVDAC2 are localized in distinct domains, whereas hVDAC3 is uniformly distributed along the mitochondrial tubules.

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