Figure 4

Frequency distribution of amino acid residues at inter-subunit interfaces of the pre-pore Cry4Aa trimer. Frequencies that amino acid residues appear within a distance of 3.5 Å from the inter-subunit interfaces of three Cry4Aa monomers in the pre-pore trimer during 10-ns MD simulations. The dotted line at frequency of 2,980 is used to indicate amino acid residues that are in contact 100% of the simulation time while the dotted line at 2,100 is for 70%.