Cryo-Transmission Electron Microscopy micrographs of non-lamellar lipid nanoparticles. Inverse bicontinuous cubic phase nanoparticles viewed along the  (A) and  (B) directions. The Fourier transforms of magnified areas shown in the right-lower inserts of each micrographs are consistent with a body centered cubic phase Im3m. The nanoparticles are made up of a dispersion of glycerol monooleate (GMO), surfactants and polymeric stabilizers. (C) Sponge phase L3 nanoparticles containing diglycerol monooleate (DGMO) and glycerol dioleate (GDO). (D) Inverted hexagonal H
nanoparticles also based on DGMO and GDO but with a different fraction of stabilizer. Adapted from reference  with permission. Copyright 2005 by the American Chemical Society.