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Figure 1 | PMC Biophysics

Figure 1

From: Inverse tuning of metal binding affinity and protein stability by altering charged coordination residues in designed calcium binding proteins

Figure 1

Model structure of designed proteins. (A) Model structure of EEDDD (7E15) and the coordination design of the variants. (B) The surface potential of Ca2+-free EEDDE, calculated using DelPhi[45], shows the highly-charged Ca2+-binding location. The calculation used interior and exterior dielectric constants of 4 and 80, respectively.

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